Ethosome: A Promising Approach for Antifungal Drug Delivery

Tejashree A. Ghadge; A.S. Kulkarni; S.H. Majumdar; S.D. Chavare

doi:10.5958/2321-5844.2015.00005.9

Research Journal of Topical and Cosmetic Sciences

ISSN

2321-5844 (Online)
0976-2981 (Print)

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Ethosome: A Promising Approach for Antifungal Drug Delivery

Author(s): Tejashree A. Ghadge, A.S. Kulkarni, S.H. Majumdar, S.D. Chavare

Email(s): tejashree.ghadge77@gmail.com

DOI: 10.5958/2321-5844.2015.00005.9

Address: Tejashree A. Ghadge*, A.S. Kulkarni, S.H. Majumdar, S.D. Chavare
Satara College of Pharmacy, Satara.
*Corresponding Author

Published In: Volume - 6, Issue - 1, Year - 2015

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ABSTRACT:
Topical drug delivery system is most preferred drug delivery system. Various skin infections are treated by transdermal drug delivery system. Fungal infection on skin is most commonly found disease. To treat topical fungal infection many semisolid dosage forms like ointment, cream and gels are used. These formulations have limited therapeutic efficacy stability and safety profiles. Stratum corneum layer of skin acts as major barrier for topical formulation. Ethosomes are modified lipid carrier that helps drug to reach deep into skin. Ethosomes can be considered as one of the best replacement for carrying antifungal agent. Ethosomes contain phospholipids and high concentration of alcohol in vesicular formulation. An alcohol acts as permeation enhancer and increase permeability of skin.

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Cite this article:
Tejashree A. Ghadge, A.S. Kulkarni, S.H. Majumdar, S.D. Chavare. Ethosome: A Promising Approach for Antifungal Drug Delivery. Research J. Topical and Cosmetic Sci. 6(1):Jan.–June 2015 page 32-37. doi: 10.5958/2321-5844.2015.00005.9

Cite(Electronic):
Tejashree A. Ghadge, A.S. Kulkarni, S.H. Majumdar, S.D. Chavare. Ethosome: A Promising Approach for Antifungal Drug Delivery. Research J. Topical and Cosmetic Sci. 6(1):Jan.–June 2015 page 32-37. doi: 10.5958/2321-5844.2015.00005.9 Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2015-6-1-5

Research Journal of Topical and Cosmetic Sciences (RJTCS) is an international, peer-reviewed journal, correspondence in the fields of skin and cosmetic research....... Read more >>>

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DOI: 10.5958/2321-5844