Author(s):
Taniyaa Bakshhi, Priya Singh, Deeksha Chaturvedi, Kathika Chattopadhyay
Email(s):
dr.kathika@gmail.com
DOI:
10.52711/2321-5844.2026.00017 
Address:
Taniyaa Bakshhi1, Priya Singh2, Deeksha Chaturvedi3, Kathika Chattopadhyay4*
1MD, Bakson Group, Bakson Homoeopathic Medical College & Hospital, Greater Noida, India.
2Former Assistant Professor, Department of Homoeopathic Pharmacy, Bakson Homoeopathic Medical College & Hospital, Greater Noida, India.
3Former Associate Professor, Department of Research Methodology and Biostatistics, Bakson Homoeopathic Medical College & Hospital, Greater Noida, India.
4Professor HOD, Psychiatry, Head, Research and Development Cell, Bakson Homeopathic Medical College & Hospital, Greater Noida, India.
*Corresponding Author
Published In:
Volume - 17,
Issue - 2,
Year - 2026
ABSTRACT:
Background: Androgenetic alopecia (AGA) is the most common form of non-scarring alopecia, characterized by progressive follicular miniaturization influenced by androgenic activity. Conventional treatments such as minoxidil and finasteride are effective but may be limited by adverse effects. Homoeopathy offers a potentially safer complementary approach; however, clinical evidence remains limited. Objective: To evaluate the clinical usefulness, safety, and patient satisfaction associated with a topical homoeopathic cosmeceutical preparation—Homoeopathic Hair Reviver and Thickening Mist (HHR)—in men with AGA. Methods: A retrospective observational case series was conducted in five male patients (aged 29–59 years) diagnosed with AGA and graded using the Modified Hamilton–Norwood Classification System. Patients applied HHR topically for 13 weeks along with oral placebo and were followed up for six months. Primary outcomes included photographic assessment of hair regrowth and stabilization. Secondary outcomes comprised patient-reported satisfaction and adverse event monitoring. Results: All patients demonstrated improvement or stabilization of hair loss at six months. Photographic assessment revealed visible improvement in hair density and scalp coverage. Patient satisfaction was high, and no adverse effects were reported. Conclusion: This case series suggests that topical application of HHR may represent a safe and potentially beneficial cosmeceutical option in the management of AGA. Larger, controlled, and long-term studies are required to confirm efficacy and sustainability of outcomes.
Cite this article:
Taniyaa Bakshhi, Priya Singh, Deeksha Chaturvedi, Kathika Chattopadhyay. Usefulness of the Topical Application of a Cosmeceutical Product: A Combination of Homoeopathic Tinctures in the Management of Male Androgenetic Alopecia – A Case Series. Research Journal of Topical and Cosmetic Sciences. 2026; 17(2):109-5. doi: 10.52711/2321-5844.2026.00017
Cite(Electronic):
Taniyaa Bakshhi, Priya Singh, Deeksha Chaturvedi, Kathika Chattopadhyay. Usefulness of the Topical Application of a Cosmeceutical Product: A Combination of Homoeopathic Tinctures in the Management of Male Androgenetic Alopecia – A Case Series. Research Journal of Topical and Cosmetic Sciences. 2026; 17(2):109-5. doi: 10.52711/2321-5844.2026.00017 Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2026-17-2-2
REFERENCES:
1. Razum J, Vukasović Hlupić T. Quality of life in young men with androgenetic alopecia: a mixed methods study. J Cosmet Dermatol. 2021; 20(4): 1122–1130.
2. Avital YS, Morvay M, Gaaland M, Kemény L. Study of the international epidemiology of androgenetic alopecia in young Caucasian men using photographs from the internet. Indian J Dermatol. 2015; 60(4): 419. doi:10.4103/0019-5154.160507
3. Manabe M, Tsuboi R, Itami S, Osada SI, Amoh Y, Ito T, et al. Guidelines for the diagnosis and treatment of male-pattern and female-pattern hair loss, 2017 version. J Dermatol. 2018; 45(9): 1031–1043.
4. Müller Ramos P, Melo DF, Radwanski H, Almeida RFC, Miot HA. Female pattern hair loss: therapeutic update. An Bras Dermatol. 2023; 98(4): e202209006.
5. Ntshingila S, Oputu O, Arowolo AT, Khumalo NP. Androgenetic alopecia: an update. JAAD Int. 2023; 13: 150–158. doi:10.1016/ j.jdin.2023.07.005
6. Umar S, Carter MJ. A multimodal hair-loss treatment strategy using a new topical phytoactive formulation: a report of five cases. Case Rep Dermatol Med. 2021; 2021: 1–12.
7. Cranwell W, Sinclair R. Male androgenetic alopecia. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2016.
8. Price VH. Androgenetic alopecia in women. J Investig Dermatol Symp Proc. 2003; 8(1): 24–27.
9. Adamowicz R, Załęcki P, Dukiel A, Nowicka D. Association between androgenetic alopecia and psychosocial disease burden: a cross-sectional survey among Polish men. Dermatol Res Pract. 2022; 2022: 1845044.
10. Qiu J, Yi Y, Jiang L, Miao Y, Jia J, Zou J, et al. Efficacy assessment for low-level laser therapy in androgenetic alopecia: a real-world study. Lasers Med Sci. 2022; 37(6): 2589–2594.
11. Natarelli N, Gahoonia N, Sivamani RK. Integrative and mechanistic approach to the hair growth cycle and hair loss. J Clin Med. 2023; 12(3): 893. doi:10.3390/jcm12030893
12. Deng Y, Wang M, He Y, Liu F, Chen L, Xiong X. Cellular senescence: ageing and androgenetic alopecia. Dermatology. 2023; 239(4): 533–541.
13. Chen S, Xie X, Zhang G, Zhang Y. Comorbidities in androgenetic alopecia: a comprehensive review. Dermatol Ther. 2022; 12(10): 2233–2247.
14. Shams H, Khan MM, Koneru A. A critical analysis of herbal products used for alopecia. Biosci Biotechnol Res Asia. 2023; 20(2): 561–570.
15. Park SY, Kim KB, Ahn SH, Kim HH. Effects of SM-215 on androgenetic alopecia. Res J Pharm Technol. 2018; 11(5): 1745–1751.
16. Rahangdale PC, Wankhade AM. Review on types and treatment of alopecia. Asian J Pharm Res. 2023; 13(2): 123–128.
17. Mustarichie R, Wicaksono IA, Hayati C. Anti-alopecia characteristics of Malvaviscus arboreus. Res J Pharm Technol. 2018; 11(11): 5066–5072.
18. Suresh PK, Ramkar S. Androgenic alopecia: molecular mechanisms and pharmacotherapy. Res J Pharm Technol. 2024; 17(12): 6137–6145.
19. Rajapaksha U, Katuwavila NPK. Medical remedies for alopecia. Res J Topical Cosmet Sci. 2024; 15(2): 107–112.
20. Kidangazhiathmana A, Santhosh P. Pathogenesis of androgenetic alopecia. Clin Dermatol Rev. 2022; 6(2): 69–75.
21. Bajoria PS, Dave P, Rohit RK, Tibrewal C, Modi N, Gandhi S, et al. Current therapeutic modalities of androgenic alopecia: a review. Cureus. 2023; 15(7): e42511.
22. Dhariwala MY, Ravikumar P. Herbal alternatives in androgenetic alopecia. J Cosmet Dermatol. 2019; 18(4): 966–975.
23. Hosking AM, Juhasz M, Mesinkovska NA. Complementary and alternative treatments for alopecia. Skin Appendage Disord. 2019; 5(2): 72–89.
24. McCoy J, Ziering C. Botanical extracts for treatment of androgenetic alopecia. Dermatol Ther. 2018; 31(6): e12794.
25. Sadgrove NJ. Plant-based remedies and 5α-reductase inhibition in AGA. J Ethnopharmacol. 2018; 227: 206–236.
26. Pekmezci E, Dündar C, Türkoğlu M. Proprietary herbal extract in androgenetic alopecia. Acta Dermatovenerol Alp Pannonica Adriat. 2018; 27(2): 51–57.
27. Comparative analysis of absorbance value of homoeopathic hair oils. Int J Pharm Res. 2021; 13(2): 1090–1095.
28. Bhadoriya YS, Jain A. Safety and efficacy of hair grow serum. Int J Herbal Med. 2023; 11(4): 01–06.
29. Prospect of herbs as hair growth potential. Res J Pharmacogn Phytochem. 2017; 9(1): 15–22.
30. Singh P. Pharmacovigilance in homoeopathy. Homoeopath Links. 2022; 35(1): 31–36.
31. Times of India. 90% of Indians prefer allopathy over AYUSH. 2015 Jul 8.
32. Fanian F, Meunier P, Bumbea D, Dahel K, Humbert P. Botanical topical serum in AGA. J Cosmet Dermatol Sci Appl. 2022; 12(1): 51–66.
33. Katoulis AC, Liakou AI, Alevizou A, et al. Botanical topical in female AGA. Skin Appendage Disord. 2018; 4(3): 160–165.
34. Vaja PN, Popaniya HS, Tank CJ, et al. Herbal approaches to reversing alopecia. Asian J Pharm Res. 2024; 14(4): 397–402.
35. Pawar AR, Vikhe DN, Jadhav RS. Advances in herbal extraction techniques. Asian J Res Pharm Sci. 2020; 10(4): 287–292.
36. Jaunjal P, Katolkar P. Herbs to treat alopecia. Asian J Pharm Technol. 2022; 12(2): 151–158.
37. Kumar N, Singh S, Gupta R. Hair growth activity of Trichosanthes dioica. Res J Pharmacogn Phytochem. 2011; 3(1): 30–33.
38. Sethi AK, Alam F, Mishra SR. Medicinal plants for hair loss. Res J Pharm Technol. 2023; 16(11): 5497–5505.
39. Khumalo NP, Gumedze F. Adapted classification of male pattern hair loss. Dermatology. 2012; 225(2): 110–114.
40. Dutta A. PITCH statement: reporting case series in homoeopathy. J Ayurveda Integr Med. 2024; 15(5): 101023.
41. Malik N. Research papers on combination homoeopathic medicines. 2012.
42. Clarke JH. A Dictionary of Practical Materia Medica. New Delhi: B Jain Publishers; 1997.
43. Boericke W. Pocket Manual of Homoeopathic Materia Medica. New Delhi: B Jain Publishers; 1998.
44. Farrington E. Lectures on Clinical Materia Medica. New Delhi: B Jain Publishers; 2010.
45. Clarke JH. A Dictionary of Practical Materia Medica. Vol 2. New Delhi: B Jain Publishers; 1995.
46. Greiner JV, Glonek T. Muscarinic receptor stimulation. Invest Ophthalmol Vis Sci. 1990; 31(9): 1814–1822.
47. Knuesel O, Weber M, Suter A. Arnica gel in osteoarthritis. Adv Ther. 2002; 19(5): 209–218.
48. Widrig R, Suter A, Saller R, Melzer J. Arnica vs NSAID topical. Rheumatol Int. 2007; 27(6): 585–591.
49. Murata K, Noguchi T, Kondo M, et al. Rosmarinic acid and hair growth. Phytother Res. 2012; 26(4): 534–538.
50. Hay IC, Jamieson M, Ormerod AD. Aromatherapy in alopecia areata. Arch Dermatol. 1998; 134(11): 1349–1352.
51. Takeda R, Ueda M, Tsuchiya Y, et al. 5α-reductase inhibition by rosemary. Biol Pharm Bull. 1998; 21(7): 751–754.
52. Nesterova IV, Kovalenko SI, Komissarenko AN. Quinine pharmacology. Exp Clin Pharmacol. 2000; 63(1): 58–61.
53. Le Gall F, Favot L, Foucault-Bertaud A, et al. Cantharidin skin response. Arch Dermatol Res. 2000; 292(11): 573–580.
54. Müller K, Ziereis K. Cantharidin and epidermal regeneration. Planta Med. 1994; 60(1): 18–21.
55. Salman KE, Altunay IK, Kucukunal NA, Cerman AA. Frequency of AGA. An Bras Dermatol. 2017; 92(1): 35–40.
56. Tosti A, Piraccini BM, Iorizzo M, Voudouris S. Natural history of AGA. J Cosmet Dermatol. 2005; 4(1): 41–43.
57. Heilmann S, Kiefer AK, Fricker N, et al. Genetic risk loci in AGA. J Invest Dermatol. 2013; 133(6): 1489–1496.
58. Liu LP, Wariboko MA, Hu X, et al. Early-onset AGA factors. PLoS One. 2024; 19(3): e0299212.