Author(s):
Shashank Nayak N, Akanksha, Ashwini S K, Manoj M J, Srusti B, Shwetha S, Kamath K, Thimmasetty J
Email(s):
shashanknayak87@gmail.com
DOI:
10.52711/2321-5844.2024.00004 
Address:
Shashank Nayak N1, Akanksha2, Ashwini S K3, Manoj M J4, Srusti B5, Shwetha S6, Kamath K6, Thimmasetty J7
1Associate Professor, Department of Pharmaceutics, Bapuji Pharmacy College, SS Layout, Shamanur Road, Davanagere, India. Affiliated to Rajiv Gandhi University of Health Sciences, Bengaluru, Karnataka.
2Final year B Pharm Student, Bapuji Pharmacy College, SS Layout, Shamanur Road, Davanagere, India. Affiliated to Rajiv Gandhi University of Health Sciences, Bengaluru, Karnataka.
3Final year B Pharm Student, Bapuji Pharmacy College, SS Layout, Shamanur Road, Davanagere, India. Affiliated to Rajiv Gandhi University of Health Sciences, Bengaluru, Karnataka.
4Final year B Pharm Student, Bapuji Pharmacy College, SS Layout, Shamanur Road, Davanagere, India. Affiliated to Rajiv Gandhi University of Health Sciences, Bengaluru, Karnataka.
5Final year B Pharm Student, Bapuji Pharmacy College, SS Layout, Shamanur Road, Davanagere, India. Affiliated to Rajiv Gandhi University of Health
Published In:
Volume - 15,
Issue - 1,
Year - 2024
ABSTRACT:
In the present investigation, melt-pour and cold-process soaps were made using various Moringa oleifera components, including seed oil, leaf powder, and leaf extracted oil. The produced soaps properties like pH, foaming capacity, foam retention, Total fatty content (TFM), saponification value, and anti-microbial activity, were determined. The 3%, 4%, and 5% moringa seed oil, leaf powder, and leaf extracted oil were used to make the soaps, and the 5% soap made using the melt-pour and cold-process method had the most promising outcomes. Considering these findings, the 5% cold process soaps were made employing the Soapcalc calculator. As advised by the soapcalc calculator, the following ingredients were utilised in this method: moringa powder, moringa seed oil, moringa leaf extract, cocoa butter, coconut oil, castor oil, olive oil, and NaOH lye. Results from the cold process experiment were satisfactory. The foam height was determined to be between 5 and 24 ml, the pH of the prepared soap was between 8.24to10.04, and the zone of inhibition of the prepared soaps for E. coli and Klebsiella was between 14 mm and 27 mm. The TFM of the prepared soap F1 to F9 was 19.6, this indicated that the melt and pour base had lower TFM. Furthermore, formulation F10 to F12 had the TFM in the range of 55.9 to 58.7. The saponification value of F10 to F12 was in the range of 27.73 to 62.74.
Cite this article:
Shashank Nayak N, Akanksha, Ashwini S K, Manoj M J, Srusti B, Shwetha S, Kamath K, Thimmasetty J. Formulation and evaluation of antibacterial Moringa soap prepared by Melt pour and Cold process method. Research Journal of Topical and Cosmetic Sciences. 2024; 15(1):20-6. doi: 10.52711/2321-5844.2024.00004
Cite(Electronic):
Shashank Nayak N, Akanksha, Ashwini S K, Manoj M J, Srusti B, Shwetha S, Kamath K, Thimmasetty J. Formulation and evaluation of antibacterial Moringa soap prepared by Melt pour and Cold process method. Research Journal of Topical and Cosmetic Sciences. 2024; 15(1):20-6. doi: 10.52711/2321-5844.2024.00004 Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2024-15-1-4
REFERENCES:
1. Islam Z, Islam SMR, Hossen F, Mahtab-Ul-Islam K, Hasan MR, Karim R. Moringa oleifera is a Prominent Source of Nutrients with Potential Health Benefits. Internation Journal of Food Science. 2021 Aug 10; 2021: 6627265. doi: 10.1155/2021/6627265. PMID: 34423026; PMCID: PMC8373516.
2. Vergara-Jimenez M, et al., Bioactive components in Moringa oleifera leaves protect against chronic disease. Antioxidants (basal). 2017 Nov 16; 6(4): 91.Doi: 10.3390/antiox6040091.PMID: 29144438; PMCID: PMC5745501
3. Shashank Nayak N., et al., Application of Soapcalc Calculator in the Design, Development and Evaluation of Exfoliating Botanical Soaps Prepared by Melt Pour Method and Cold Process Method. Indian Journal of Natural Sciences. 2023; 14(79): 60595-60605.
4. Yongbing Xu, Potential anti-aging components from Moringa oleifera leaves explored by affinity ultrafiltration with multiple drug targets. Frontiers in Nutrition. 2022 May 10; 9: 854882. doi: 10.3389/fnut.2022.854882
5. Athikomkulchai S, Tunit P, Tadtong S, Jantrawut P, Sommano SR, Chittasupho C. Moringa oleifera Seed Oil Formulation Physical Stability and Chemical Constituents for Enhancing Skin Hydration and Antioxidant Activity. Cosmetics. 2021; 8(1): 2. https://doi.org/10.3390/cosmetics8010002
6. Abera BH, Diro A, Beyene TT. The synergistic effect of waste cooking oil and endod (Phytolacca dodecandra) on the production of high-grade laundry soap. Heliyon. 2023 Jun 1; 9(6): e16889. doi: 10.1016/j.heliyon. 2023.e16889. PMID: 37346337; PMCID: PMC10279813.
7. Suchitra G, Ganesh V, Siva Krishna B, et al. Formulation and Evaluation of Poly Herbal Anti-Bacterial Soap. International Journal of of Engineering Science and Computing. 2020; 10(8): 27165-173.
8. Rakesh K. Sindhu, Mansi Chitkara, Gagandeep Kaur. Formulation Development and Anti-Microbial Evaluation of Polyherbal Soap. Plant Archives. 2019. 19 (Supplement 2): 1342-46.
9. Mathapathi, M. S, Mallemalla, P, Vora, S, IyerV, Tiwari J. K, Chakrabortty A, Majumdar, A. Niacinamide leave-on formulation provides long-lasting protection against bacteria in vivo 2017. Experimental Dermatology. 26(9): 827–829. doi:10.1111/exd.13285
10. Andrew Setiawan Rusdianto, et al., The Characteristics of Liquid Soap with Additional Variations of Moringa Seed Extract (Moringa oleifera L.), International Journal on Food, Agriculture, and Natural Resources. 2021; 2(3): 5-11.
11. Purohit M.C, Anuj K, Reena P, Semwal A.R, Parveen S, Arun K.K. Antimicrobial Activity of Synthesized Zinc Oxide Nanoparticles using Ajuga bracteosa Leaf Extract. Asian Journal of Pharmaceutical Analysis. 2021; 11(4): 275-80.
12. Rakesh P, Sujit.In Vitro Antibacterial Activity of Leaf Extracts of Hibiscus Syriacus (L). Research Journal of Topical and Cosmetic Sciences. 2014; 5(2): 51-55.
13. Arti P P, Dhanashri N P, Yogita V. D. Formulation and Evaluation of Polyherbal Soap. 2019; 10(1): 23-28. DOI: 10.5958/2321-5844.2019.00006.2
14. Samiksha V. Amrutkar, Ashwini R. Patil, Suraj K. Ishikar. A Review on Herbal Soap. Research Journal of Topical and Cosmetic Sciences. 2022; 13(1): 49-4. doi: 10.52711/2321-5844.2022.00008.
15. Arushi Pant, Shriya Agarwal, Manisha Singh. Bacteriostatic activity of Melaleuca alternifolia loaded Microemulsion targeting microbial skin infection by Topical Delivery. Research J. Topical and Cosmetic Sci. 2019; 10(2): 48-56. doi: 10.5958/2321-5844.2019.00011.6.
16. Shiny Ganji, A. Chandrika, S. Mounika, K. Kusuma, D. Jyothsna Kumari, M. Sampada. Formulation and Evaluation of Polyherbal Cream. Research Journal of Topical and Cosmetic Sciences. 2022; 13(2): 57-1. doi: 10.52711/2321-5844.2022.00009.
17. Nanda Badhe, Lina Shirode, Shivam Lale. Formulation and Evaluation of Herbal Hair Tonic. Research J. Topical and Cosmetic Sci. 2015; 6(2): 86-90. doi: 10.5958/2321-5844.2015.00012.6.
18. Ghurghure S M, Dhange A A, Kamalapure N R, Kate S N, Katkar A R, Katta A V, Kattimani C U, Kattimani S G. Formulation and Evaluation of Herbal Hand Wash Gel using Nerium oleander. Research J. Topical and Cosmetic Sci. 2019; 10(1): 1-6. doi: 10.5958/2321-5844.2019.00001.3.