Author(s): Nitin Gosavi, Dhananjay D. Chaudhari, Dipak E. Jagdale, Neha R. Jaiswal

Email(s): nitingosavi2000@gmail.com

DOI: 10.52711/2321-5844.2023.00006   

Address: Nitin Gosavi*, Dhananjay D. Chaudhari, Dipak E. Jagdale, Neha R. Jaiswal
Ahinsa Institute of Pharmacy, Dondaicha, Shindkheda, Dhule, 425408 India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 1,     Year - 2023


ABSTRACT:
Herbal formulations always have attracted considerable attention because of their good activity and comparatively lesser or nil side effects with synthetic drugs. The objective of present study involves preparation of herbal hair oil using amla, hibiscus, bhringraj, methi and its evaluation for increase in hair growth activity. Each drug was tested for their hair growth activity in a concentration range for 1-10% separately. Based on these results mixture of crude drugs fruits of Embelica officinalis, flowers of Hibiscus rosa sinensis, leaves of Bacopa monnieri and seeds of Trigonella techniques (direct boiling, paste and cloth method) and were tested for hair growth activity. The oil of different concentrations were characterized for proximate analysis including moisture content, total ash, acid insoluble ash, water soluble ash, water insoluble ash, sulphated ash. The formulations were also subjected to chromatographic determination and chemical tests to determine the presence of active constituents in the drugs. But looking towards the formulation viscosity the maximum concentration of combined drug was found to be 30% at their maximum level. The formulation containing 7.5% of each drug used for the study and showed excellent hair growth activity with standard (2% minoxidil ethanolic solution) by an enlargement of follicular size and prolongation of the anagen phase. It holds the promise of potent herbal alternative for minoxidil. Excellent results of hair growth were seen in formulation prepared by boiling method of oils preparation technique.


Cite this article:
Nitin Gosavi, Dhananjay D. Chaudhari, Dipak E. Jagdale, Neha R. Jaiswal. Formulation and Evaluation of Polyherbal Lotus Oil. Research Journal of Topical and Cosmetic Sciences. 2023; 14(1):29-4. doi: 10.52711/2321-5844.2023.00006

Cite(Electronic):
Nitin Gosavi, Dhananjay D. Chaudhari, Dipak E. Jagdale, Neha R. Jaiswal. Formulation and Evaluation of Polyherbal Lotus Oil. Research Journal of Topical and Cosmetic Sciences. 2023; 14(1):29-4. doi: 10.52711/2321-5844.2023.00006   Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2023-14-1-6


REFERENCE:
1.    Kokate C.K, Purohit A.P and Gokhale S.B. Pharmacognosy, Nirali Publication.
2.    Indian Pharmacopoeia- 1996, Ministry Of Health And Family Welfare, Controller Of Publications, Govt. Of India, Volume 1: A- 78 Ions.
3.    Roy, R. K., Thakur, M., Dixit, V. K., Development And Evaluation Of Polyherbal Formulation For Hair Growth- Promoting Activity, Journal of Cosmetic Dermatology, Nov2006, 6, 108-112.
4.    B. M. Mithal and R. N. Shah, A Hand Book Of Cosmetics, 1st Edition, Vallabh Prakashan, Delhi (2000) Pp. 141-142.
5.    Indian Pharmacopoeia, Government Of India, Ministry Of Health And Family Welfare, Published By, The Controller Of Publication, Edition, Vol. II (1996).
6.    Kokate CK, Purohit AP and Gokhale SB. Pharmacognosy, Nirali Publications.2008; 42:10.41-10.46.
7.    Yadav P, Harisha CR and Prajapati PK. Pharmacognostical And Physicochemical Evaluation of Agasti Leaf. Int J Ayurveda Res. 1(4):231–236.
8.    Indian Pharmacopoeia- 1996, Ministry of Health and Family Welfare, Controller of Publications, Govt. Of India, Volume 1: A- 78.
9.    Khandelwal KR. Practical Pharmacognosy Techniques and Experiments, Nirali Publication, Pune. 2009;9:157-161.
10.    Sunita Verma. Hibiscus Rosa-Sinesismultipurpose Ornamental Plant. International Journal of Research In Pharmacology And Pharmacotherapeutics.2016; 6(1):61-64.
11.    Roji Bista, Arjun Ghimire and Sadikshyasubedi. Phytochemicals And Antioxidant Activities of Aloe Vera. Journal Of Nutritional Sciences and Healthy Diet 2020; 1(1):25-36.
12.    Banerjee PS, Sharma M, Kumar RN. Preparation, Evaluation and Hair Growth Stimulating Activity Of Herbal Hair Oil. J. Chempharm Res.2009; 1(1):261-267.
13.    Mahmoud Bahmani, Hedayatollahshirzad, Mahmoud Mirhosseini, MD, Endocrinologist, Azadehmesripour and Mahmoud Rafieian-Kopaei; Journal Of EvidenceBased Complementary and Alternative Medicine; A Review On Ethnobotanical And Therapeutic Uses Of Fenugreek (Trigonellafoenum-Graceum L); Vol. 21.
14.    Sajad Ahmad Wani, Pradyumankumar; Journal Of The Saudi Society Of Agricultural Sciences; Fenugreek: A Review On Its Nutraceutical Properties And Utilization In Various Food Products.
15.    Https://Www.Herbalkart.In/2013/07/Tulasi-Tulsi-Ocimum-Sanctum.Html?M=1
16.    KP Sampath Kumar, Debjitb howmik, Biswajit, Chiranjib, Pankaj and KK Tripathi Margret Chandira; Research J. Pharmacognosy and Phytochemistry; Traditional Indian Herbal Plants Tulsi and Its Medicinal Importance; ISSN 0975- 2331.
17.    Jena Jitendra, Tripathivineeta, Kumar Ashok, Kumar Brijesh and Pankajsingh; International Journal Of Research In Pharmacy and Chemistry; Rosa Centifolia: Plant Review; Issn: 2231-2781.
18.    Randal VA, Botchkareva NV. The Biology of Hair Growth. In: Ahluwalia GS, Editor. Cosmetic Application of Laser and Light Based System. Norwich, NY: William Andrew Inc. 2009. Pp. 3–35.
19.    Blume-Peytavi U, Vogt A. Human Hair Follicle: Reservoir Function and Selective Targeting. Br J Dermatol 2011;165:13–17.
20.    Oshima H, Rochat A, Kedzia C Et Al. Morphogenesis and Renewal Of Hair Follicles From Adult Multipotent Stem Cells. Cell 2001;104: 233–245.
21.    Ito M, Kizawa K, Hamada K Et Al. Hair Follicle Stem Cells In The Lower Bulge Form The Secondary Germ, A Biochemically Distinct But Functionally Equivalent Progenitor Cell Population, At The Termination Of Catagen. Differentiation 2004;72: 548–557.
22.    Cotseralis G, Sun TT, Lavker RM. Label-Retaining Cells Reside In The Bulge Area Of Pilosebaceous Unit: Implications For Follicular Stem Cells, Hair Cycle, And Skin Carcinogenesis. Cell 1990; 61: 1329–1337.
23.    Rothnagel JA, Roop DR. Hair Follicle Companion Layer: Reacquainting An Old Friend.  J Invest Dermatol 1995; 104: 42S–43S.
24.    Rogers MA, Langbein L, Praetzer-Wundel S Et Al. Human Hair Keratin Associated Proteins (Kaps). Int Rev Cytol 2006; 251:209–263.
25.    Jankovic SM, Jankovic SV. The Control of Hair Growth. Dermatol Online J 1998;4:2.
26.    Jahoda CA, Reynolds AJ. Dermal-Epidermal Interactions. Adult Follicle Derived Cell Populations and Hair Growth. Dermatol Clin 1996;14:573–583.
27.    Paus R, Müller-Röver S, Botchkarev VA. Chronobiology of The Hair Follicle: Hunting The “Hair Cycle Clock”. J Invest Dermatol Symp Proc 1999;4: 338–345.
28.    Peus D, Pittelkow MR. Growth Factors In Hair Organ Development And The Hair Growth Cycle. Dermatol Clin 1996; 14: 559–572.
29.    Roger GE. Hair Follicle Differantiation And Regulation. Int J Dev Biol 2004; 48:163– 170.
30.    Christoph T, Müller-Röver S, Audring H Et Al. The Human Hair Follicle Immun System: Cellular Compositon And Immunprivilage. Br J Dermatol 2000;142: 862–873.
31.    Ito T. Hair Follicle Is A Target Of Stress Hormone And Autoimmune Reactions. J Dermatol Sci 2010; 60: 67–73.
32.    Paus R, Ito N, Takigawa M Et Al. The Hair Follicle And Immune Privilege. J Investig Dermatol Symp Proc 2003; 8:188–194.
33.    Thibaut S, Gaillard O, Bouhanna P Et Al. Human Hair Shape Is Programmed From The Bulb. Br J Dermatol 2005;152:632–638.
34.    Schneider MR, Schmidt-Ulrich R, Paus R. The Hair Follicle As A Dynamic Miniorgan.  Currbiol 2009;19: R132–R142.
35.    Kligman AM. The Human Hair Cycle. J Invest Dermatol 1959;33:307–316.
36.    Paus R, Foitzik K. In Search of The “Hair Cycle Clock”: A Guided Tour.Differentiation 2004;72:489–511.
37.    Greco V, Chen T, Rendl M Et Al. A Two-Step Mechanism For Stem Cell Activation During Hair Regeneration. Cell Stem Cell 2009;4:155–169.
38.    Paus R. Principles of Hair Cycle Control. J Dermatol 1998;25:793–802.
39.    Trüeb RM. Swiss Trichology Study Group. The Value of Hair Cosmetics And Pharmaceuticals. Dermatology. 2001;202:275–82.  
40.    Trüeb RM. Dermocosmetic Aspects Of Hair And Scalp. J Investig Dermatol Symp Proc. 2005;10:289–92.  
41.    Schwartz JR, Henry JP, Kerr KM, Flagler MJ, Page SH, Redman-Furey N, Et Al.  Incubatory Environment Of The Scalp Impacts Pre-Emergent Hair To Affect Post-Emergent Hair Cuticle Integrity. J Cosmet Dermatol. 2018;17:105–11. \
42.    Trüeb RM. Aging Of Hair. J Cosmet Dermatol. 2005;4:60–72.  
43.    Piérard-Franchimont C, Uhoda I, Saint-Léger D, Piérard GE. Androgenetic Alopecia and Stress-Induced Premature Senescence By Cumulative Ultraviolet Light Exposure. Exog Dermatol. 2002;1:203–6.  
44.    Piérard GE, Piérard-Franchimont C, Nikkels-Tassoudji N. Improvement In The Inflammatory Aspect of Androgenetic Alopecia. A Pilot Study With An Antimicrobial Lotion. J Dermatol Treat. 1996;7:153–7.  
45.    Piérard-Franchimont C, De Doncker P, Cauwe, Nbergh G, Piérard GE. Ketoconazole Shampoo: Effect of Long-Term Use In Androgenic Alopecia. Dermatology. 1998;196: 474–7.
46.    Yamini N Sudha Ss, Formulation and Evaluation of Polyherbal Hair Oil Pharmacognosy Phytochem. 20187;32546
47.    Chatwal GR And Anand Sk. Refractrometry, Instrumental Method of Chemical Amalysis Publishing House, Chandigarh, 2004;36;2.566-2.587 

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