Author(s):
Diksha K. Nunse, Rohini N. Jadhav, Amol S. Deshmukh
Email(s):
dikshanunse@gmail.com
DOI:
10.52711/2321-5844.2022.00006 
Address:
Diksha K. Nunse*, Rohini N. Jadhav, Amol S. Deshmukh
Department of Pharmaceutics, SMBT College of Pharmacy, Nandi - Hills, Dhamangaon, Tal - Igatpuri, Dist - Nashik, Pin - 422403, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 1,
Year - 2022
ABSTRACT:
Creams are a type of pharmaceutical product used for daily skin care, as well as medicated and non-medicated applications. It is also regarded as a vital component of cosmetics. When the dosage form is creams, the route of delivery is the skin. The rate of medication absorption and penetration is influenced by a variety of factors in the skin. The topical medication delivery system is a method of delivering drugs to the skin. Topical medication administration has the advantage of bypassing first-pass metabolism, hydrating the skin, and providing emollient qualities. Creams are viscous or semisolid emulsions that come in O/W or W/O dosage forms and have a viscosity that changes depending on the quantities of oil and water in them. In terms of functions and qualities, there is a vast range of creams available. Pharmaceutical creams are used for a range of purposes, including cleansing, beautifying, hydrating, and protecting against bacteria and fungi, as well as treating skin wounds. Water, fats, waxes, emollients, colors, scents, and other common ingredients are employed in the creation of practically every cream, resulting in a standard formulation. There are various evaluation parameters available for creams which help the product to match its standard quality eg. pH, viscosity, stability, spreadability, etc.
Cite this article:
Diksha K. Nunse, Rohini N. Jadhav, Amol S. Deshmukh. Cream as a Drug Delivery System for Topical Diseases. Research Journal of Topical and Cosmetic Sciences. 2022; 13(1):35-3. doi: 10.52711/2321-5844.2022.00006
Cite(Electronic):
Diksha K. Nunse, Rohini N. Jadhav, Amol S. Deshmukh. Cream as a Drug Delivery System for Topical Diseases. Research Journal of Topical and Cosmetic Sciences. 2022; 13(1):35-3. doi: 10.52711/2321-5844.2022.00006 Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2022-13-1-6
REFERENCES:
1. Ashni V, Sukhdev S, Rupinder K, Upendra J. Topical gels as Drug delivery system: A review. Pharmaceutical Sciences Review and Research. Nov-Dec 2013; 23(2): 374-382.
2. Pratiksha R, Adarsh P, Sujit D. Pharmaceutical creams and their use in wound healing: A review. Journal of Drug Delivery and Therapeutics. 2019; 9(3-5): 907-912.
3. JamshiyaSahmsu. Formulation and evaluation of herbal skin cream for Wound Healing. 2017
4. AK Mohiuddin. Skin care creams: formulation and use. America Journal of of Dermatological Research and Reviews. 2019 2:8.
5. Tarun G, Goutam R, Amit G. Comparative review on additives of topical dosage forms for Drug Delivery. 2015; 22(8), 969-987, DOI: 10.3109/10717544.2013.879355.
6. Anchal S, Swarnima P, Arpita S, Siddique A, Nitish P. Creams: A topical drug delivery system (TDDS). Europen Journal of Pharmaceutical and Medical Research. 2021; 8(1): 340-342.
7. Lalita C, Shalini G. Creams: A review on classification, preparation methods, Evaluation and its application. Journal of Drug Delivery and Therapeutic. 2020; 10(5-5): 281-289.
8. Tanesh S, Trun P, Sagar S, Bina G. Skin cream as topical drug delivery system. Journal of Pharmaceutical and Biological Sciences 2016; 4(5): 149-154.
9. James Q, Del R, Jacquelyn L. Skin structure and function: Translation of Research to Patient Care. 2011; 4(9): 22-42.
10. Mohiuddin AK. Cosmetics in use: A pharmacological review. Journal of Dermatology and Cosmetology. 2019; 3(2) : 50-67.
11. Hagar L, Labiba EI-K, Tobias K and Marc S. Mechanism and determinants of nanoparticles through human skin. 2011; 3:4989-499, DOI: 10.1039/clnr11109d.
12. Pinaki D, Ram P, Mandip S. Interaction of nanoparticles and cell penerality peptides with skin for transdermal drug delivery. 2010; 27(7): 247-259, DOI: 10.3109/09687688.2010.522203.
13. Mahdi R, Elise L, Samuel B, Davide B. A snapshot of transdermal and topical drug delivery research in Canada. 2019; 11:256. DOI: 10.3390/ Pharmaceutics11060256.
14. Larissa P, Dominique L. Film forming systems for dermal drug delivery. 2021; 13: 932.
15. Benedetta S, Ivan Z, Roberta M et al. Cream formulation impact on topical administration of engineered colloidal nanoparticles. 2015: 1-14, DOI: 10.1371/journal.phone.0126366.
16. Ashish A, Mohini K, Abhiram R. Prepartion and evaluatin of polyherbal cosmetic cream. 2013; 5(1): 83-88.
17. Sameeha K, Shalaka A, Ashwin K, Ashwini G. A mini review- Pharmaceutical creams. 2021; 10(4): 60-62. DOI: 10.36347/SAJP.2021.V10i04.001.
18. Vinod S, Kris D, Gary E ,et al. Topical and transdermal products. 2009; 35(3): 750-764.
19. Tais G, Ulrich S, Lihong J, Mingyann G, et al. Penetration of quantum dot particles through human skin. 2010; 6: 586-595.
20. James Q, Del R. The role of skin care and maintaining proper barrier function in the management of Rosacea. 2007; 20(8): 485-489
21. Ahmad O, A del M, Ali M, Mohammad T. Topical application of aloevera accelerated wound healing, modeling and remoulding. 2016; 77(1): 37-46.
22. Susan Wijnhoven. Interaction of inorganic nanoparticles with the skin barrier. National Instuite for Public Health and the Environment. 2-42.
23. Dr. M.S Darade, Dr. S. Muthukumar, Dr. M.S. Kadam, Mr. R. Shrivastava; Research & development in pharmaceutical science; Bhumi Publishing; 1st Edition 2021.
24. Saima j, Sabiha K, Muhammad, et al. Anti ageing potential of phytoextrect loaded pjarmaceiutical creams for human skin cell longetivity. 2015;2-17, DOI: 101155/2015/709628.
25. Z.D Draelos, L.A Thamen; Cosmetic formulation of skin care Products; Taylor & Francis group.
26. Christian S, Nina D, Jan K. Skin care product for healthy and diseased skin. 2018; 54: 183-200. DOI: 101159/000489532.
27. Ashish D, Amit U, Naveen S, Ravish S et al. Optimization of formulation and process parameter and product evaluation of Galatomannan- Borate complex based cream. Research Journal of Pharmaceutical Dosage Form and Technology. 2009; 1(3): 229-232.
28. Vani M, Mounika K, Vamsi T, Praneetha K, et al. Formulation phytochemical, physical, biological evaluation of polyherbal vanishing cream and facewash. Research Journal of Pharmaceutical Dosage Form and Technology. 2020; 12(3): 139-149. DOI: 10.5958/0975-4377.2020.00024.5
29. Shikha A, Yogesh S. Formulation and evaluation of herbal cream containing extract of Ziziphus jujube leaves for analgesic potential. Research Journal of pharmaceutical Dosage Forms and Technology. 2012; 4(6): 320-323.