ABSTRACT:
This article proposes a novel formula for determining the Sun Protection Factor (SPF) of topical sunscreens by extending the classical spectrophotometric model. Unlike the traditional Mansur equation, which focuses on UVB radiation, this method is widely accepted for in vitro SPF determination, it has notable limitations. Primarily, it focuses solely on UVB radiation, neglecting UVA rays that penetrate deeper into the skin and contribute significantly to photoaging and carcinogenesis. The new model incorporates a broader ultraviolet spectrum (290–400 nm) and introduces an improved weighting function to represent both erythemal and photoaging risks. This method enhances SPF accuracy and aligns more closely with real-world exposure.
Cite this article:
Sachin Gangadhar Lokapure. A New Sun Protection Factor Equation-Integrating Erythemal and Photoaging Risks across Biological and Space UV Exposure. Research Journal of Topical and Cosmetic Sciences. 2026; 17(1):11-4. doi: 10.52711/2321-5844.2026.00003
Cite(Electronic):
Sachin Gangadhar Lokapure. A New Sun Protection Factor Equation-Integrating Erythemal and Photoaging Risks across Biological and Space UV Exposure. Research Journal of Topical and Cosmetic Sciences. 2026; 17(1):11-4. doi: 10.52711/2321-5844.2026.00003 Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2026-17-1-3
8. REFERENCES:
1. Sana Tabassum, Ajitha M. Quantitative Spectrophotometric Estimation of Prednisolone in Tablet Dosage Form Using Eco-friendly Green Solvent and by applying Beer-Lambert’s Law Mathematical Equation Method. Asian Journal of Research in Chemistry. 2021; 14(3): 155-0. doi: 10.52711/0974-4150.2021.00029.
2. Yarguntla. Kikuchi-Fujimoto Disease: A Rare Lymphadenitis with Diagnostic Challenges and Treatment Considerations. Asian Journal of Research in Pharmaceutical Sciences. 2024; 14(2): 129-6. doi: 10.52711/2231-5659.2024.00019.
3. Parag Sukare, Rupa Bhattacharya. Herbal plant used in Treatment of Psoriasis - A Systematic Review. Res. J. Pharmacognosy and Phytochem. 2020; 12(1): 57-62. doi: 10.5958/0975-4385.2020.00011.4
4. Sowmya Annavarapu, Merry Raphael, Vijayanarayana K, Girish Thunga, Sreedharan N. A Study on Clinical Manifestations, Treatment Pattern and Outcome in Systemic Lupus Erythematosus Patients in Tertiary Care Hospital. Research J. Pharm. and Tech. 2017; 10(5): 1383-1388. doi: 10.5958/0974-360X.2017.00246.3
5. Strus Oksana, Polovko Nataliia, Maloshtan Liudmyla, Shakina Liubov. Study of Anti-inflammatory activity of medicinal products with Sapropel extract on the model of Acute photodynamic skin injury in rats. Research J. Pharm. and Tech. 2020; 13(9):4381-4386. doi: 10.5958/0974-360X.2020.00774.X
6. Nurdiana, Tri Wahyudi Iman Dantara, Mokhamad Fahmi Rizki Syaban, Siti Asyifa Mustafa, Hanifah Ikhsani, Febrinda Esti Syafitri, Novi Kurnia Hapsari, Auliya Khoirunnisa. Effect of Bryophyllum pinnatum Leaves Ethanol Extract in TNF-α and TGF-β as Candidate Therapy of SLE in Pristane-Induced SLE BALB/c Mice Model. Research J. Pharm. and Tech. 2021; 14(2):1069-1072. doi: 10.5958/0974-360X.2021.00192.X
7. Shruti Rathore, Alpana Ram, Dipesh Lall, Bhagyashree Agrawal, Pranay Soni, Mohd Javed Naim. Development and Evaluation of Sunscreen Cream Containing Benzophenone-3 Microspheres for Enhancing Sunscreen Activity. Research Journal of Pharmacy and Technology. 2021; 14(11): 6078-4. doi: 10.52711/0974-360X.2021.01056
8. Ankit Loya, Latha K, Naseeb Basha Shaik, Aisha Rahman, Javeria Tamkeen. Formulation and Evaluation of Transdermal Gel loaded with Atenolol. Research Journal of Pharmacy and Technology. 2023; 16(5):2265-2. doi: 10.52711/0974-360X.2023.00372
9. Bitan Naik, Mahima Yadav, Vikas Kailashiya, Anu Singh, Sandip Kumar. Prevalence of Antineutrophil cytoplasmic Antibodies in Systemic Lupus Erythematosus and its relevance with Clinical manifestations. Research Journal of Pharmacy and Technology. 2024; 17(10): 5065-0. doi: 10.52711/0974-360X.2024.00779
10. Tilottama M. Gatkine, Vaishnavi S. Shete, Nilesh M. Mahajan, Ujwala N. Mahajan. Potential of phyto-constituents as a skin tanning agents. Research J. Topical and Cosmetic Sci. 2019; 10(1):34-38. doi: 10.5958/2321-5844.2019.00008.6.
11. Ichihashi M, Ueda M, Budiyanto A, Bito T, Oka M, Fukunaga M, Tsuru K, Horikawa T. UV-induced skin damage. Toxicology. 2003; 189(1–2): 21–39. doi:10.1016/S0300-483X(03)00150-1
12. Lu H, Edwards C, Gaskell S, Pearse A, Marks R. Melanin content and distribution in the surface corneocyte with skin phototypes. Br J Dermatol. 1996; 135(2): 263–267. doi:10.1111/j.1365-2133.1996.tb01157.x
13. Saraf S, Ashawat M. Anti-solar activity of flower extract of Rosa damascena and Tagetes erecta Linn. Planta Indica. 2005; 1:26–27.
14. Teixeira CC, Rava CA, Silva PM, Melchior R, Argenta R, Anselmi F, Almeida CR, Fuchs FD. Absence of antihyperglycemic effect of jambolan in experimental and clinical models. J Ethnopharmacol. 2000; 71(1–2): 343–347. doi:10.1016/S0378-8741(00)00185-9
15. Rahman AU, Zaman K. Medicinal plants with hypoglycemic activity. J Ethnopharmacol. 1989; 26(1): 1–55. doi:10.1016/0378-8741(89)90112-8
16. Mansur JS, Breder MNR, Mansur MCA, Azulay RD. Correlação entre a determinação do fator de proteção solar em seres humanos e por espectrofotometria. An Bras Dermatol. 1986; 61: 167–172.
17. Mansur JS, Breder MNR, Mansur MCA, Azulay RD. Determinação do fator de proteção solar por espectrofotometria. An Bras Dermatol. 1986; 61: 121–124.
18. Sayre RM, Agin PP, LeVee GJ, Marlowe E. A comparison of in vivo and in vitro testing of sunscreening formulas. Photochem Photobiol. 1979; 29(3): 559–566. doi:10.1111/j.1751-1097.1979.tb07090.x
19. Diffey BL. Solar ultraviolet radiation effects on biological systems. Phys Med Biol. 1991; 36(3): 299–328.