Author(s): Zohra Firdous, Pankaj Dhapake, Nitin Padole, Nilakshi Dhoble, Jagdish Baheti

Email(s): zohrafirdous.143@gmail.com

DOI: 10.52711/2321-5844.2023.00015   

Address: Zohra Firdous*, Pankaj Dhapake, Nitin Padole, Nilakshi Dhoble, Jagdish Baheti
Department of Pharmaceutics, Kamla Nehru College of Pharmacy, Butibori, Nagpur 441108, Maharashtra, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2023


ABSTRACT:
Transdermal drug delivery is a validated technology that makes a significant contribution to global pharmaceutical care. Since 1980, the sector has seen impressive growth with several commercial successes. The term transdermal drug delivery refers to the delivery of a drug across the layers of skin with the intention of allowing the drug to be absorbed through the skin in a predetermined and controlled rate manner. Skin is one of the largest organs that act as an efficient barrier for drug delivery. The present study focuses on the different approaches of nano-carrier system that delivers the nano-carrier drug across the skin barrier with the help of transdermal delivery system. Nano-carrier drug delivery systems are one of the biggest challenges to deliver drug into systemic circulation by crossing the skin barrier providing a passive drug delivery strategy that is known to be safer and faster than the conventional method. In this review, we describe the diverse types of nano-carriers approaches that have been synthesized for transdermal delivery system includes liposomes, niosomes, ethosomes, solid lipid nanoparticles (SLN), nanostructured lipid carrier (NLC), polymeric nanoparticles, nanocrystals, nanofibers and nanosuspension/nanoemulsion. Several characterization methods of transdermal delivery system have been proposed to control the behavior of nano-carriers, along with in-vitro and in-vivo and other evaluation parameters. It was concluded that the compatibility of nano-carriers with the skin structure should be considered for transdermal nanocarrier delivery systems, which will be the most preferred route for drug delivery in the future as it offers high patient compliance, controlled dosing, low frequency of dosing, high physico-chemical stability and better dermal bioavailability, etc.


Cite this article:
Zohra Firdous, Pankaj Dhapake, Nitin Padole, Nilakshi Dhoble, Jagdish Baheti. Different Approaches for Transdermal Nano-Carrier Delivery System. Research Journal of Topical and Cosmetic Sciences. 2023; 14(2):94-4. doi: 10.52711/2321-5844.2023.00015

Cite(Electronic):
Zohra Firdous, Pankaj Dhapake, Nitin Padole, Nilakshi Dhoble, Jagdish Baheti. Different Approaches for Transdermal Nano-Carrier Delivery System. Research Journal of Topical and Cosmetic Sciences. 2023; 14(2):94-4. doi: 10.52711/2321-5844.2023.00015   Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2023-14-2-8


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