Author(s): Jemima Daniela Shultz, Amanda C. Caritá, Hana Mohd, Bozena Michniak-Kohn, Laura Moretti Aiello, Gislaine Ricci Leonardi

Email(s): gislaine.leonardi@fcf.unicamp.br

DOI: 10.52711/2321-5844.2022.00002   

Address: Jemima Daniela Shultz1, Amanda C. Caritá2, Hana Mohd3, Bozena Michniak-Kohn4, Laura Moretti Aiello5, Gislaine Ricci Leonardi6
1,2Medicine Department, Graduate Program in Translational Medicine, Federal University of Sao Paulo, Rua Pedro de Toledo, 720 - 2º Floor, Zip Code: 01039032, São Paulo (SP), Brazil.
1,3,4Center for Dermal Research, The State University of New Jersey – Rutgers, 145 Bevier Rd, Piscataway, NJ 08854, USA.
5,6Faculty of Pharmaceutical Science, University of Campinas - Unicamp, Rua Cândido Portinari, 200, Zip Code: 13083-859, Campinas (SP), Brazil.
*Corresponding Author

Published In:   Volume - 13,      Issue - 1,     Year - 2022


ABSTRACT:
Vitamin C (ascorbic acid) is widely used in skin care products, yet it is a challenging compound due to its physical and chemical instability. Several strategies have been applied to improve the stability of vitamin C, such as the addition of other antioxidants in the system (e.g., Vitamin E, ferulic acid, and sodium metabisulfite). In addition, clay minerals have been used in cosmetic preparations due to their high ion-exchange capacity, thermal stability, softness, the small size of their particles, and their attractive adsorptive properties. In this study, we proposed the association of kaolin clay and well-known antioxidants and chelators to improve the stability of vitamin C. Although the kaolin clay alone did not improve the stability of the vitamin C, the clay mineral in association with certain chelators and/or antioxidants could improve the stability of formulations containing vitamin C.


Cite this article:
Jemima Daniela Shultz, Amanda C. Caritá, Hana Mohd, Bozena Michniak-Kohn, Laura Moretti Aiello, Gislaine Ricci Leonardi. Cosmetics Formulations containing Vitamin C and The Instability Challenge. Research Journal of Topical and Cosmetic Sciences. 2022; 13(1):9-3. doi: 10.52711/2321-5844.2022.00002

Cite(Electronic):
Jemima Daniela Shultz, Amanda C. Caritá, Hana Mohd, Bozena Michniak-Kohn, Laura Moretti Aiello, Gislaine Ricci Leonardi. Cosmetics Formulations containing Vitamin C and The Instability Challenge. Research Journal of Topical and Cosmetic Sciences. 2022; 13(1):9-3. doi: 10.52711/2321-5844.2022.00002   Available on: https://rjtcsonline.com/AbstractView.aspx?PID=2022-13-1-2


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