Malvastrum coromandelianum belongs to Malvaceae family, commonly known as the false mallow. Ethnobotanical survey reported its use in the treatment of various disorders. Pharmacological screening has shown the plant to have anti-inflammatory, analgesic, and antibacterial activity. Antioxidants or inhibitors of oxidation are compounds which retard or prevent the oxidation and in general prolong the life of the oxidizable matter. Majority of the diseases/disorders are mainly linked to oxidative stress due to free radicals. The free radicals (oxidants) are species with very short half-life, high reactivity and damaging activity towards macromolecules like proteins, DNA and lipids. In general, the reactive oxygen species circulating in the body tend to react with the electron of other molecules in the body and these also effect various enzyme systems and cause damage which may further contribute to conditions such as cancer, ischemia, aging, adult respiratory distress syndromes, rheumatoid arthritis etc. A plant-based diet protects against chronic oxidative stress-related diseases. Dietary plants contain variable chemical families and amounts of antioxidants. It has been hypothesized that plant antioxidants may contribute to the beneficial health effects of dietary plants. The results of the free radical scavenging activity of the DPPH radical assay method for antioxidant activity have shown that the Malvastrum coromandelianum leaf extracts exhibits significant scavenging activity.
Cite this article:
Akshay R. Yadav, Shrinivas K. Mohite. Antioxidant Activity of Malvastrum coromandelianum Leaf extracts. Research J. Topical and Cosmetic Sci. 2020; 11(2):59-61. doi: 10.5958/2321-5844.2020.00010.2
Akshay R. Yadav, Shrinivas K. Mohite. Antioxidant Activity of Malvastrum coromandelianum Leaf extracts. Research J. Topical and Cosmetic Sci. 2020; 11(2):59-61. doi: 10.5958/2321-5844.2020.00010.2 Available on: http://rjtcsonline.com/AbstractView.aspx?PID=2020-11-2-2
1. Sittiwet C, Jesadanont S, Pongpech P, Naenna P, Pongsamart S. Antibacterial activity of Malvastrum coromandelianum Garcke against methicillin-sensitive and methicillin-resistant strains of Staphylococcus aureus. Current Res Bacteriol. 2008; 1(1): 42-45.
2. Srivastava S.N, Kapoor LD, Singh A, Kapoor S. Survey of Indian plants for saponins, alkaloids and flavonoids I. Lloydia. 1969; 32: 297-304.
3. Kallapa M, Raviraj S, Dheeraj, A moderate source of cyclopropenoid fatty acids in Malvastrum tricuspidatum. Medicinal Aromatic Plant Sci Biotech. 2004; 26(2): 53-56.
4. Kirtikar K, Basu B. Indian Medicinal Plants. Vol. 1. Dehra Dun, India: International Book Distributors and Publishers; 1995: 304-308.
5. Yadav A, Mohite S. Anticancer Activity and In-Silico ADMET Analysis of Malvastrum Coromandelianum. International Journal of Pharma Sciences and Research. 2020; 11
6. Jain P, Bansal D, Bhasin P, Anjali. Antimicrobial activity and phytochemical screening of five wild plants against Escherichia coli, Bacillus subtilis and Staphylococcus aureus, J Pharm Res. 2010; 3: 1260‑1262.
7. Acharya R, Padiya RH, Patel ED, Rudrapa HC, Shukla VJ, Chauhan MG Pharmacognostical evaluation of leaf of Bada Rasna [Nelsonia canescens (Lam.) Spreng.; Acanthaceae]. Anc Sci Life. 2012; 31: 194‑197.
8. Gawade SP, Chandrashekar Rao MV. Antihepatotoxic activities of Ci compound: β sitosterol isolated from fruits and leaves of Coccinia indica. Indian J Pharm Educ Res 2012; 46: 4‑8.
9. Hatano T, Edamatsu R, Mori A, Fujita Y, Yasuhara E. Effects of tannins and related polyphenols on superoxide anion radical and on 1, 1‑diphenyl‑2‑picrylhydrazyl. Chem Pharm Bull. 1989; 37: 2016‑2023.
10. Yadav A, Mohite S. Screening of In-vitro anti-inflammatory and Antibacterial assay of Malvastrum Coromandelianum. International Journal of Pharma Sciences and Research. 2020, 11(4): 68-70.
11. Vishwananthan B, Gurupadayya B, Sairam K, Inturi B. Design, synthesis, In vitro antioxidant and in vivo anti-inflammatory activities of novel oxadiazole derivatives. Int J Pharm Pharm Sci. 2014; 6(9): 514-520.
12. Adesegun SA, Fajana A, Orabueze CI, Coker HA. Evaluation of antioxidant properties of phaulopsis fascisepala C.B.Cl. (Acanthaceae). Evid Based Complement Alternat Med. 2009, 6: 227‑231.