Volume No. :   6

Issue No. :  2

Year :  2015

ISSN Print :  0976-2981

ISSN Online :  2321-5844


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An Updated Review on Formulation and Evaluation of Microsponge

Address:   Audumbar Digambar Mali*, Ritesh Bathe
Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola- 413307, Solapur, Maharashtra, India.
*Corresponding Author
DOI No: 10.5958/2321-5844.2015.00011.4

Microsponges are polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles with a large porous surface. Moreover, they may enhance stability, reduce side effects and modify drug release favorably. Microsponge technology has many favorable characteristics, which make it a versatile drug delivery vehicle. Microsponge Systems are based on microscopic, polymer-based microspheres that can suspend or entrap a wide variety of substances, and can then be incorporated into a formulated product such as a gel, cream, liquid or powder. Microsponge and Nanosponge delivery System was originally developed for topical delivery of drugs can also be used for controlled oral delivery of drugs using water soluble and bioerodible polymers. Microsponge delivery system (MDS) can entrap wide range of drugs and then release them onto the skin over a time by difussion mechanism to the skin. It is a unique technology for the controlled release of topical agents and consists of nano or micro porous beads loaded with active agent and also use for oral delivery of drugs using bioerodible polymers.
Microsponges, Controlled release, Porous microspheres, Nanosponge, Solvent Diffusion Method, Quasi-Emulsion Method.
Audumbar Digambar Mali, Ritesh Bathe. An Updated Review on Formulation and Evaluation of Microsponge. Research J. Topical and Cosmetic Sci. 6(2): July-Dec. 2015 page 77-85.
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