Volume No. :   6

Issue No. :  1

Year :  2015

ISSN Print :  0976-2981

ISSN Online :  2321-5844


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Evaluation of Wound Healing Effect of Polyherbal Ointment in Alloxan Induced Diabetic Rats



Address:   Sayeed ul hasan S.M1*, Nitin Mahurkar2
1Department of Pharmacology, Sai Pranavi College of Pharmacy, Keesara, RR Dist., Hyderabad, Andhra Pradesh, India
2Department of Pharmacology, HKES College of Pharmacy, Gulbarga, Karnataka, India
*Corresponding Author
DOI No: 10.5958/2321-5844.2015.00006.0

ABSTRACT:
To design a polyherbal ointment and assess its wound healing property in alloxan induced diabetic rats. Based on the literature survey, 04 plants with proven wound healing property were selected; the parts of the plants were collected and subjected to extractions using ethanol as solvent. The herbal extracts obtained were incorporated in a simple ointment base by fusion method. Wistar albino rats weighing between 180-200g of either sex were used for screening the polyherbal ointment. Diabetes was induced chemically using alloxan (150mg/kg; i.p.) and the wound healing property was assessed by excision wound model. The results were statistically interpreted by one way ANOVA followed by Dunnett’s test and were compared with that of standard ointment formulation framycetin. From the results, it is clearly evident that the polyherbal ointment posses significant wound healing effect in diabetic rats. Thus, it is concluded that the designed Polyherbal ointment is an effective wound healing formulation..
KEYWORDS:
Polyherbal Ointment, Wound healing activity, Alloxan Induced Diabetes.
Cite:
Sayeed ul hasan S.M, Nitin Mahurkar. Evaluation of Wound Healing Effect of Polyherbal Ointment in Alloxan Induced Diabetic Rats. Research J. Topical and Cosmetic Sci. 6(1):Jan.–June 2015 page 38-43.
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