Volume No. :   6

Issue No. :  1

Year :  2015

ISSN Print :  0976-2981

ISSN Online :  2321-5844


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Ethosome: A Promising Approach for Antifungal Drug Delivery



Address:   Tejashree A. Ghadge*, A.S. Kulkarni, S.H. Majumdar, S.D. Chavare
Satara College of Pharmacy, Satara.
*Corresponding Author
DOI No: 10.5958/2321-5844.2015.00005.9

ABSTRACT:
Topical drug delivery system is most preferred drug delivery system. Various skin infections are treated by transdermal drug delivery system. Fungal infection on skin is most commonly found disease. To treat topical fungal infection many semisolid dosage forms like ointment, cream and gels are used. These formulations have limited therapeutic efficacy stability and safety profiles. Stratum corneum layer of skin acts as major barrier for topical formulation. Ethosomes are modified lipid carrier that helps drug to reach deep into skin. Ethosomes can be considered as one of the best replacement for carrying antifungal agent. Ethosomes contain phospholipids and high concentration of alcohol in vesicular formulation. An alcohol acts as permeation enhancer and increase permeability of skin.
KEYWORDS:
Antifungal, Ethosome, Phospholipids, Lipid carrier, Vesicular system.
Cite:
Tejashree A. Ghadge, A.S. Kulkarni, S.H. Majumdar, S.D. Chavare. Ethosome: A Promising Approach for Antifungal Drug Delivery. Research J. Topical and Cosmetic Sci. 6(1):Jan.–June 2015 page 32-37.
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